Tag Archives: blood

US recommends ‘pause’ for J&J vaccine over clot reports

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WASHINGTON (AP) – The U.S. is recommending a “pause” in administration of the single-dose Johnson & Johnson COVID-19 vaccine to investigate reports of potentially dangerous blood clots.

In a joint statement Tuesday, the Centers for Disease Control and Prevention and the Food and Drug Administration said they were investigating clots in six women that occurred 6 to 13 days after vaccination. The clots were observed in the sinuses of the brain along with reduced platelet counts – making the usual treatment for blood clots, the blood thinner heparin, potentially “dangerous.”

More than 6.8 million doses of the J&J vaccine have been administered in the U.S., the vast majority with no or mild side effects.

U.S. federal distribution channels, including mass vaccination sites, will pause the use of the J&J shot, and states and other providers are expected to follow. The other two authorized vaccines, from Moderna and Pfizer, make up the vast share of COVID-19 shots administered in the U.S. and are not affected by the pause.

CDC’s Advisory Committee on Immunization Practices will meet Wednesday to discuss the cases and the FDA has also launched an investigation into the cause of the clots and low platelet counts.

“Until that process is complete, we are recommending a pause in the use of this vaccine out of an abundance of caution,” Dr. Anne Schuchat, principal deputy director of the CDC, and Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said in a joint statement.

They are recommending that people who were given the J&J vaccine who are experiencing severe headache, abdominal pain, leg pain, or shortness of breath within three weeks after receiving the shot contact their health care provider.

Officials say they also want to educate vaccine providers and health professionals about the “unique treatment” required for this type of clot.

Johnson & Johnson said it was aware of the reports of “thromboembolic events,” or blood clots, but that no link to its vaccine had been established.

“We are aware that thromboembolic events including those with thrombocytopenia have been reported with Covid-19 vaccines,” said Johnson & Johnson in a statement. “At present, no clear causal relationship has been established between these rare events and the Janssen Covid-19 vaccine.”

The J&J vaccine received emergency use authorization from the FDA in late February with great fanfare, with hopes that its single-dose and relatively simple storage requirements would speed vaccinations across the country. Yet the shot only makes up a small fraction of the doses administered in the U.S. as J&J has been plagued by production delays and manufacturing errors at the Baltimore plant of a contractor.

Last week the drugmaker took over the facility to scale up production in hopes of meeting its commitment to the U.S. government of providing about 100 million doses by the end of May.

Only about 9 million of the company’s doses have been delivered to states and are awaiting administration, according to CDC data.

Until now concern about the unusual blood clots has centered on the vaccine from AstraZeneca, which has not yet received authorization in the U.S. Last week, European regulators said they found a possible link between the shots and a very rare type of blood clot that occurs together with low blood platelets, one that seems to occur more in younger people.

The European Medicines Agency stressed that the benefits of receiving the vaccine outweigh the risks for most people. But several countries have imposed limits on who can receive the vaccine; Britain recommended that people under 30 be offered alternatives.

But the J&J and AstraZeneca vaccines are made with the same technology. Leading COVID-19 vaccines train the body to recognize the spike protein that coats the outer surface of the coronavirus. But the J&J and AstraZeneca vaccines use a cold virus, called an adenovirus, to carry the spike gene into the body. J&J uses a human adenovirus to create its vaccine while AstraZeneca uses a chimpanzee version.

The announcement hit U.S. stock markets immediately, with Dow futures falling almost 200 points just over two hours before the opening bell. Shares of Johnson & Johnson dropped almost 3%

Missouri State hosts annual Spring Blood Drive

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SPRINGFIELD, Mo. – Missouri State University and the American Red Cross will hold its annual Spring Blood Drive March 23, 24 & 25 at the Foster Rec Center (945 E. Madison) from 10 a.m. to 3 p.m.

If you book your appointment using the sponsor code “MSU,” you can get a Red Cross T-shirt. Appointments can be booked at redcrossblood.org, download the Red Cross Blood Donor App or call 1-800-REDCROSS.

The Cherokee Nation acknowledges that descendants of people once enslaved by the tribe should also qualify as Cherokee

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TAHLEQUAH, Okla. – A longstanding dispute over who can be considered a citizen of the Cherokee Nation finally came to a conclusion this week.

The Cherokee Nation Supreme Court ruled on Monday that the tribal nation remove the phrase “by blood” from its constitution and other tribal laws. That change formally acknowledges that the descendants of Black people once enslaved by the tribe — known as the Cherokee Freedmen — have the right to tribal citizenship, which means they are eligible to run for tribal office and access resources such as tribal health care.

The recent decision by the Cherokee Nation Supreme Court is a response to a 2017 ruling by a US district court, which determined that the descendants of the Cherokee Freedmen are entitled to full tribal citizenship rights under a treaty the Cherokee Nation made with the US in 1866.

“Freedmen rights are inherent,” Cherokee Nation Supreme Court Justice Shawna S. Baker wrote in the opinion. “They extend to descendents of Freedmen as a birthright springing from their ancestors’ oppression and displacement as people of color recorded and memorialized in Article 9 of the 1866 Treaty.”

Enslaved Black people journeyed on the Trail of Tears

The history of the Cherokee Freedmen is an example of just how complex and layered issues of race, inequality and marginalization are in the US.

Many Native Americans were enslaved alongside African Americans during the colonial period — Brown University historian Linford D. Fisher estimates that 2 million to 5.5 million Native people were enslaved from the time of Christopher Columbus to around 1880.

But some wealthier tribal citizens, particularly in tribes in the Southeast that had adopted certain norms of White settlers, also practiced slavery themselves. That includes the Cherokee people, some of whom in the early 1800s had started to enslave African Americans.

Then in the late 1830s, the US government forcibly expelled the Cherokee from their homeland and ordered them to relocate to present-day Oklahoma — an exodus known as the Trail of Tears. What’s not as widely known, though, is that enslaved African Americans made the journey along with the Cherokee citizens who enslaved them.

About 4,000 enslaved Black people were living among the Cherokee people by 1861, according to the National Museum of the American Indian.

The tribe abolished slavery in 1863. And shortly after the Civil War ended, the Cherokee Nation signed a treaty with the US government that granted full citizenship rights to those formerly enslaved by Cherokee citizens.

But in practice, Freedmen were often denied those rights and excluded from the tribe, wrote Lolita Buckner Inniss in a 2015 article published in the Columbia Journal of Race and Law. Over the past several decades, Cherokee Freedmen have fought to protect those rights through various legal proceedings.

Freedmen have long been fighting to protect their rights

In 2007, the Cherokee Nation amended its constitution to restrict tribal citizenship to those with “Indian blood.” That expelled about 2,800 descendants of Cherokee Freedmen from the tribe, the website for the National Museum of the American Indian states.

Chad Smith, the principal chief of the Cherokee Nation at the time, argued that the tribe was a sovereign nation and should therefore have the right to determine who qualifies for tribal citizenship. But the Freedmen pushed back, resulting in a series of legal battles over the next decade.

In 2017, a federal district court ruled in favor of the Freedmen — a decision that the Cherokee Nation Supreme Court has now reaffirmed.

“The ‘by blood’ language found within the Cherokee Nation Constitution, and any laws which flow from that language, is illegal, obsolete, and repugnant to the ideal of liberty,” Baker wrote in the recent opinion. “These words insult and degrade the descendants of the Freedman much like the Jim Crow laws found lingering on the books in Southern states some fifty-seven years after the passage of the 1964 Civil Rights Act.”

Cherokee Nation Principal Chief Chuck Hoskin Jr. commended the decision.

“Cherokee Nation is stronger when we move forward as citizens together and on an equal basis under the law,” he said in a statement on Monday. “…The court has acknowledged, in the strongest terms, our ancestors’ commitment to equality 155 years ago in the Treaty of 1866. My hope is that we all share in that same commitment going forward.”

About 8,500 descendants of Freedmen are currently enrolled as citizens of the Cherokee Nation, according to a news release from the tribe.